Prepositionary
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The correct preposition(s) for:

SUPPOSE (V)

We all supposed him to be German, but in fact he was Swiss. (Cambridge dictionary)

The procedure supposes that a will has already been proved. (Oxford dictionary)

The correct preposition(s) for:SACCHARINE

His panegyric on his company president was too saccharine for my taste.

The correct preposition(s) for:SACRED

The correct preposition(s) for:SACRIFICE (N)

They made a sacrifice of their lives.

“The religion of patriotism: the worship of the Nation as the supreme object of affection: the sacrifice of general unity to local feeling.” (Hilaire Belloc, Richelieu)

The correct preposition(s) for:SACRIFICE (V)

They’re sacrificing their present comfort for their long term security.

He refused to sacrifice objectivity to the flow of his narrative.

The correct preposition(s) for:SAD

I’m sad about that turn of events.

The correct preposition(s) for:SADDLE (V)

The correct preposition(s) for:SAFE

I really thought my house was safe against fire.

Granny was safe at home.

please keep me safe from all harm.

His money was safe in his pocket.

I think it’s safe to go on.

The child felt safe with her elder sister.

The correct preposition(s) for:SAIL (V)

I’m sailing (i.e. leaving by ship) for England tomorrow. “Then all the great people sailed in state (i.e. went in a dignified manner) from the room.” (C. Bronte, Universal Oxford Dictionary)

They sail (i.e. travel the sea) on a gorgeous yacht.

She sailed (i.e. navigated) solo to Liverpool, then to Amsterdam.

The correct preposition(s) for:SAKE

growth for the sake of growth is the ideology of the cancer cell.” (Edward Abbey quoted in The Nine Nations of North America)

The correct preposition(s) for:SALE

The sale of that famous painting was an even more famous scam.

I would have forbidden that sale to her for any of a dozen reasons.